Journal: Materials Today Bio

Article Title: Generating tolerance through in situ recruitment of regulatory T cells for allogeneic cell transplantation in a bioengineered lymphoid platform

doi: 10.1016/j.mtbio.2025.102469

Figure Lengend Snippet: NanoLymph design and characterization. (A) Cross-section rendering of NanoLymph device with view of drug and cell reservoirs, silicone drug loading ports on opposing sides, and collagen scaffold. (B) NanoLymph shown to scale in comparison with commercially available M&M TM ; scale bar, 5 mm. (C) SEM image of new polyethersulfone (PES) nanoporous membrane; scale bar, 5 μm. (D) SEM image of PES nanoporous membrane after 9 months of in vivo implantation; scale bar, 5 μm. (E) SEM image of new nylon woven mesh; scale bar 300 μm. (F) SEM image of nylon mesh after 9 months of in vivo implantation; scale bar 300 μm.

Article Snippet: Nylon nanoporous membranes (100 nm, GVS Filter Technology, Bologna, Italy), polyethersulfone (PES) nanoporous membranes (30 nm; Sterlitech, Washington, US), and nylon meshes (100 μm, 300 μm; GVS Filter Technology, Bologna, Italy) produced using a laser cutter (VLS 2.30, Universal Laser Systems, Arizona, USA) were sterilized by autoclave and then heat pressed at 300 °F for 30 min using the Cricut EasyPress 2.

Techniques: Comparison, Membrane, In Vivo